NOVA CLEANSE Disinfectant Solution
Neutral Electrolyzed Water - NaOCl, HOCl
What is Neutral Electrolyzed Water (NEW) ?
Neutral Electrolyzed Water (‘NEW’) is an all-natural, organic, non-toxic, non-irritant, environmentally and ecologically safe sanitizing and disinfecting solution. Neutral Electrolyzed Water (NEW) is made by passing an electric current through a solution of water and a small amount of salt ( approx.. 0.2 ~ 0.3%) in a process known as electrolysis. NEW is composed of NaOCl & HOCl generated in the water electrochemically. The disinfectant water generation system product low concentrations of NaOCl & HOCl ( 100 ~ 200 ppm ) water. At this concentration, NaOCl & HOCl are “ Generally Recognized as Safe “ (GRAS) by the FDA for food contact surfaces & sanitizing rinse for approved food. The applications for this technology are infinite and include any process requiring a sterilizing, disinfecting, cleaning or water purification facility.
What is Hypochlorous Acid, HOCl? And why is it so effective?
HOCl is an endogenous substance in all mammals and is effective against a broad range of microorganisms. Neutrophils, eosinophils, mononuclear phagocytes, and B lymphocytes produce HOCl in response to injury and infection through the mitochondrial membrane–bound enzyme known as “respiratory burst nicotinamide adenine dinucleotide phosphate oxidase.” HOCl selectively binds with the unsaturated lipid layer and subsequently disrupts cellular integrity. Between pH levels of 3 and 6, the predominant species is HOCl that has maximal antimicrobial properties.
HOCl is a powerful oxidizing agent. In aqueous solution, it dissociates into H+ and OCl–, denaturing and aggregating proteins. HOCl also destroys viruses by chlorination by forming chloramines and nitrogen-centered radicals, resulting in single- as well as double-stranded DNA breaks, rendering the nucleic acid useless and the virus harmless.
An ideal disinfectant and sanitizer must be nontoxic to surface contact, noncorrosive, effective in various forms, and relatively inexpensive. HOCl may be the disinfectant of choice for coronaviruses in an oral-maxillofacial surgery (OMS) office.
FIG 1
Inactivation of human NoV without (A) and with (B) additional soil load following a 1-min exposure to neutral electrolyzed water (NEW) in suspension assay followed by RT-qPCR. Black and gray bars indicate samples with and without an RNase pretreatment prior to RNA extraction and amplification, respectively. Experiments were performed in triplicate, and error bars indicate standard error. Different letters show statistically significant differences (P < 0.05) when comparing log10 reduction in genomic copies by concentration of NEW for samples without (a, b, c) and with (x, y, z) RNase pretreatment. The dashed lines indicate the highest quantifiable degree of virus log10 inactivation based on assay limit of detection.
